You might be able to accomplish that by using a combination of our standard Cart buttons, non-javascript Cart buttons, and Buy Now buttons.
When your page uses our standard E-junkie Cart button codes including at least one complete block of View Cart code, the cart displays as an overlay "inside" your page and sets cart-tracking cookies with your own domain.
When your page uses our non-javascript E-junkie Cart button codes, or if the page is using the standard codes but merely missing the javascript portion of your View Cart code, the Cart buttons in that page will work in "fallback mode" by displaying the cart in a separate window/tab, which sets cart-tracking cookies with our "e-junkie.com" domain.
As such, because of those differing cart cookie domains, items added to an overlay cart "inside" your page would not appear in the fallback cart, and vice-versa.
Finally, Buy Now buttons bypass the cart entirely and take buyers directly to instant checkout for just one item at a time. This means tax/shipping charges cannot be calculated in the cart before checkout, and only Discount Codes with certain settings can work with Buy Now buttons:
http://www.e-junkie.com/ej/faq.discounts.buy-now.htm